By Jonathan Latham, PhD and Allison Wilson, PhD

This text was originally posted as a Twitter/X thread. We are reposting it (minus a few typos) as a short essay.

1/ Many people on Twitter are, like Nicholas Wade, wondering if the latest DEFUSE grant revelations from @emilyakopp and @USRTK are maybe the last word on the great #covidorigin #lableak debate. They are not.

2/ Why? Because they only deepen the mystery. The short answer is that six hallmark sites of reverse engineering identified by Bruttel et al: ( only explain 0.1% or less of the #SARS-CoV-2 genome.More